The Department of Physiology is one of the core departments in the College of Medicine at King Saud University, established in 1391 AH (1971 AD) as a distinguished academic foundation in the field of health sciences in the Kingdom of Saudi Arabia. The department contributes to the university's and the nation's vision and mission by providing high-quality education and advanced research that supports the development of the healthcare sector.

The department is responsible for teaching physiology to medical students and students from other health-related colleges, such as Dentistry, Pharmacy, and Nursing. It emphasizes equipping them with in-depth knowledge and skills that enhance their professional capabilities. Additionally, it offers graduate programs (Master's and Ph.D.) in collaboration with the Center for Postgraduate Medical Education, preparing researchers and academic professionals.

The department is committed to applying the highest academic and scientific standards across its programs, aligning with local and international accreditation requirements. It fosters innovation and excellence to ensure the graduation of healthcare professionals capable of addressing future challenges. Moreover, the department supervise clinical physiology unit at King Abdulaziz University Hospital and seeks to strengthen partnerships with national and international healthcare and educational institutions to support research and curriculum development.

Aligned with Saudi Vision 2030, the department is dedicated to empowering national capacities in healthcare and promoting research that addresses societal health challenges. It strives to prepare a generation of qualified healthcare professionals and stimulate innovative scientific research that supports national health development, enhancing the quality of healthcare provided at university hospitals and amplifying its positive impact on the community and the healthcare sector.